Progression in Huntington’s disease may be due more to a gradual loss of the system that maintains the health of brain cells than to accumulated damage caused by the disease itself, a computational analysis of large and complex datasets suggests. This analysis, called Geomic, showed that while brain cells most vulnerable…
I’ve found that having a parent with Huntington’s disease makes you value every moment with them, even in unfortunate situations. For instance, normally I wouldn’t volunteer to go on a road trip from Massachusetts to Illinois, but I would for my mother. As I’ve previously written, my mom was…
The Cleveland Team Hope Walk & 5K Run is on tap for Aug. 15 to raise funds to help the Huntington’s Disease Society of America (HDSA) Northeast Ohio Chapter to improve the lives of Huntington’s disease (HD) patients and their families. The event, which seeks to raise $36,000…
“Parting is such sweet sorrow,” Shakespeare once wrote. And don’t I know it. Recently, the big news in my home is we’re moving to the East Coast, as my wife, Jill, and I want to move closer to our daughter, who lives in Boston, and other family…
Brain-derived neurotrophic factor (BDNF) may not be the biomarker for Huntington’s disease that it was previously thought to be, a recent study reported. The progressive loss of BDNF, a factor that helps neurons grow and survive, associates with Huntington’s progression in mouse disease models, and past studies found it at reduced…
Dear people working to find a cure for Huntington’s disease (HD), I imagine you all have various reasons for seeking a cure. Near the top of your list is probably a love for science and a challenge. Or, perhaps you view HD like George Huntington, whose medical observations of people…
One afternoon in May, I got a call from a number I didn’t recognize, and I rejected it immediately. Given the number of spam calls today, I wouldn’t normally log that in my memory, but then I received a voicemail from the hospital where…
A history of high alcohol intake seems to be linked to increased motor impairment and a higher burden of psychiatric symptoms in Huntington’s disease patients, a large international study suggests. The observational study, “Genetic and Environmental Contributors to Neurodegeneration: An Exploration of the Effects of Alcohol…
At its first virtual investor event, biotech company Centogene set a bold mission: to cure 100 rare diseases within the next decade. A leader in the field of genetic diagnostics, Centogene used the June 22 event to present its strategic priorities, outlining its plans to speed the discovery…
Treatment with pridopidine rescues the function of mitochondria — the cell’s powerhouses — boosting energy production, and reduces oxidative stress in models of Huntington’s disease, preclinical research shows. According to researchers, these findings support the therapeutic potential of pridopidine and its ongoing clinical development. Pridopidine is a small oral…
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