Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

November 15, 2018November 15, 2018

Compound in Raspberries May Help Protect Against Huntington’s, Other Neurodegenerative Diseases, Study Says

News

A bioactive compound present in raspberries called salidroside can prevent the cellular toxicity that occurs as a consequence of protein accumulation in certain neurodegenerative diseases, including Huntington’s disease, a study reports. ... Read more

November 1, 2018November 1, 2018

Juvenile Huntington’s More Aggressive, Leads to Early Symptoms, Study Reports

News

The juvenile form of Huntington’s disease, which affects patients younger than 20, is particularly aggressive and associated with an early onset of symptoms, a retrospective study has found. Based on ... Read more

August 2, 2018August 2, 2018

Protein May Help Prevent Nerve Cell Death in Huntington’s Disease

News

Researchers have found a protein, called UBR5, that may reduce neurodegeneration in Huntington’s disease (HD). This protein prevents the toxic aggregation (clustering) of mutant huntingtin protein, which is the underlying ... Read more

July 12, 2018July 12, 2018

Retrotope’s RT001 Reduced Cognitive Defects in Mice with Huntington’s Disease, Study Shows

News

Retrotope’s investigative therapy RT001 reduced cognition deficits in mice with Huntington’s disease, and was found to lower the amount of oxidative damage in their brains. The study, “Deuterium‐reinforced linoleic acid lowers lipid peroxidation ... Read more

June 26, 2018June 26, 2018

Dysfunction of Astrocyte Brain Cells Plays Key Role in Huntington’s, Mouse Study Suggests

News

Impaired metabolism of a type of brain cell called an astrocyte plays an important role in the development and progression of Huntington’s disease, a study using a mouse model ... Read more

June 14, 2018June 14, 2018

Huntington’s Protein Levels in Saliva May Work as Biomarker for Disease Worsening, Study Suggests

News

Elevated levels of a specific protein in the saliva of Huntington’s disease patients may be used as a biomarker to measure motor function and clinical outcomes, according to researchers. ... Read more

May 31, 2018May 31, 2018

Unexpected Link Between Huntington’s Disease and Rheumatoid Arthritis Found in Study

News

Genetic causes behind Huntington’s disease may overlap with those behind rheumatoid arthritis, an unexpected finding that could potentially open the door for new therapeutics targeting both diseases, a study suggests. The ... Read more

May 24, 2018May 24, 2018

Class of Lipids Merit ‘High Priority’ Attention as Possible Treatment Route in Huntington’s, Study Says

News

Increasing evidence links a specific fat to Huntington’s disease, and it “merits more attention” as a “high priority” target for potential disease treatments, a review study reports. The study, ... Read more

May 22, 2018May 22, 2018

Antibiotic May Protect Huntington’s Nerve Cells from Death, Mouse Study Suggests

News

Monensin, an antibiotic widely used in feed for animals like cows that chew their cud, can help protect cells against oxidative stress linked to Huntington’s disease, according to a ... Read more

May 8, 2018May 8, 2018

Blocking Gpr52 Receptor Improves Huntington’s Symptoms in Animal Models, Study Finds

News

Targeting the Gpr52 receptor can reduce the levels of mutant huntingtin (HTT) proteins and improve Huntington’s disease symptoms, including walking problems, in animal models, a study suggests. The study, ... Read more

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