Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

February 12, 2019February 12, 2019

Fast Screening Strategy Identifies Potential New Inhibitors for Huntington’s Disease

News

Several small molecules have been identified by the Alborada Drug Discovery Institute as potential inhibitors to help halt the underlying mechanisms that drive the development of neurodegenerative diseases such as Huntington’s and Parkinson’s ... Read more

January 29, 2019January 29, 2019

FDA Clears First Clinical Study of AMT-130 Gene Therapy in Huntington’s disease

News

uniQure is launching a Phase 1/2 trial in the United States to evaluate the safety and effectiveness of its Huntington’s disease investigational gene therapy AMT-130. This follows recent approval of ... Read more

January 15, 2019January 15, 2019

Asuragen Launches AmplideX as Faster Diagnostic Test for Huntington’s Disease

News

Asuragen has launched a fast, easy-to-use and reliable diagnostic test, called AmplideX PCR/CE HTT Kit, for Huntington’s disease. The AmplideX test is able to detect up to more than 200 ... Read more

January 8, 2019January 8, 2019

Most Transplanted Fetal Nerve Cells in Brain of Huntington’s Patients Do Not Thrive, Study Says

News

While transplanted fetal nerve cells can survive long term in the brain of a Huntington’s disease (HD) patient, only a specific subset called interneurons thrive, according to a study. ... Read more

November 15, 2018November 15, 2018

Compound in Raspberries May Help Protect Against Huntington’s, Other Neurodegenerative Diseases, Study Says

News

A bioactive compound present in raspberries called salidroside can prevent the cellular toxicity that occurs as a consequence of protein accumulation in certain neurodegenerative diseases, including Huntington’s disease, a study reports. ... Read more

November 1, 2018November 1, 2018

Juvenile Huntington’s More Aggressive, Leads to Early Symptoms, Study Reports

News

The juvenile form of Huntington’s disease, which affects patients younger than 20, is particularly aggressive and associated with an early onset of symptoms, a retrospective study has found. Based on ... Read more

August 2, 2018August 2, 2018

Protein May Help Prevent Nerve Cell Death in Huntington’s Disease

News

Researchers have found a protein, called UBR5, that may reduce neurodegeneration in Huntington’s disease (HD). This protein prevents the toxic aggregation (clustering) of mutant huntingtin protein, which is the underlying ... Read more

July 12, 2018July 12, 2018

Retrotope’s RT001 Reduced Cognitive Defects in Mice with Huntington’s Disease, Study Shows

News

Retrotope’s investigative therapy RT001 reduced cognition deficits in mice with Huntington’s disease, and was found to lower the amount of oxidative damage in their brains. The study, “Deuterium‐reinforced linoleic acid lowers lipid peroxidation ... Read more

June 26, 2018June 26, 2018

Dysfunction of Astrocyte Brain Cells Plays Key Role in Huntington’s, Mouse Study Suggests

News

Impaired metabolism of a type of brain cell called an astrocyte plays an important role in the development and progression of Huntington’s disease, a study using a mouse model ... Read more

June 14, 2018June 14, 2018

Huntington’s Protein Levels in Saliva May Work as Biomarker for Disease Worsening, Study Suggests

News

Elevated levels of a specific protein in the saliva of Huntington’s disease patients may be used as a biomarker to measure motor function and clinical outcomes, according to researchers. ... Read more

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