Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

November 21, 2017November 21, 2017

Rilmenidine Well-Tolerated in HD Patients, but More Studies Needed, Researchers Say

News

Researchers have found that rilmenidine, a blood pressure medicine, was relatively safe and well-tolerated by Huntington’s disease (HD) patients in a small study. However, its effectiveness in treating the disease ... Read more

November 2, 2017

Researchers Identify Mechanism to Prevent Toxic Accumulation of Proteins in Mitochondria

News

Researchers have identified an elaborate protein quality control system that prevents toxic accumulation of faulty proteins inside mitochondria, a phenomenon that underlies many neurodegenerative diseases, including Huntington’s disease. The ... Read more

October 31, 2017

Natural Compounds May Carry Therapeutical Benefits for Huntington’s

News

As therapeutics for Huntington’s disease (HD) are still a need, a number of natural compounds may hold promising beneficial effects, a review study shows. The review “The Medicinal Chemistry ... Read more

September 5, 2017September 5, 2017

Huntington’s Causes Hearing Problems, Study with a Small Sample Size Suggests

News

Huntington’s disease causes hearing problems, a study with a small sample size suggests. The research, “Auditory dysfunction in patients with Huntington’s disease,“ was published in Clinical Neurophysiology. A severe, ... Read more

August 31, 2017August 31, 2017

Researchers Create New Cell Model to Study Functions of Mutant Protein in Huntington’s

Huntington's Disease News, News

Researchers generated the first human line of Huntington’s disease induced pluripotent stem cells (iPSCs) that do not express the dysfunctional protein underlying the condition. The cells represent a potential ... Read more

August 1, 2017

Using Gene Editing to Suppress Activity of Protein Mutations Could Be Way to Treat Huntington’s, Study Reports

News

Researchers used gene editing to suppress the activity of protein mutations in the brains of mice with Huntington’s disease. Suppressing the huntingtin protein alleviated early signs of the disease ... Read more

April 13, 2017

Results of Probiodrug AG Mouse Study to be Presented at HD Therapeutics Conference

News

Probiodrug AG recently announced the results of a preclinical study investigating the role of glutaminyl cyclases (QCs) in Huntington’s disease. The results will be presented at the 12th Annual HD ... Read more

July 25, 2016July 25, 2016

Monkey Models Show Human Symptoms of Huntington’s Disease

News

Scientists at Yerkes National Primate Research Center, Emory University have shown that transgenic monkeys for Huntington’s disease exhibit early emergent symptoms, like humans with the disease, which bolsters the idea that ... Read more

April 18, 2016April 18, 2016

Researchers Decrease Accumulation of Damaging Huntington’s Disease Protein Using New Method in Mice

News

A recent study published in the journal Neuron by University of California at Irvine researchers revealed that the protein PIAS1 regulates the accumulation of a mutant protein in Huntington’s disease, and its ... Read more

January 20, 2016January 20, 2016

Depression in Huntington’s Patients Associated With Changes in Brain’s White Matter

News

Neuropsychiatric symptoms of depression and irritability or aggression are associated with alterations in the white matter structure of the brains of early-onset Huntington’s disease (HD) patients. These are the results ... Read more

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