Posts by: Marta Figueiredo

Marta Figueiredo

Marta Figueiredo holds a BSc in Biology and a MSc in Evolutionary and Developmental Biology from the University of Lisbon, Portugal. She is currently finishing her PhD in Biomedical Sciences at the University of Lisbon, where she focused her research on the role of several signalling pathways in thymus and parathyroid glands embryonic development.

November 26, 2020November 26, 2020

Survey Finds COVID-19 Disrupted Care, Well-Being of Rare Disease Patients in Europe

News, syndicated

The first wave of COVID-19 in Europe severely disrupted access to care and raised stress and anxiety in people with rare diseases, negatively affecting their health and well-being, according to ... Read more

September 29, 2020September 29, 2020

Phase 3 Trial of Oral Pridopidine in Early Stage Patients Opening Soon

News

Prilenia Therapeutics, in partnership with the Huntington Study Group (HSG), has launched the Phase 3 PROOF-HD clinical trial to evaluate the company’s lead experimental oral therapy, pridopidine, in people with ... Read more

September 15, 2020September 15, 2020

Huntington’s in Youth Closely Tied to Problems With School and Social Life

News

Behavioral changes due to early onset Huntington’s disease and problems with school, and social and family life are common, particularly among pediatric patients, according to a case series study in ... Read more

September 1, 2020September 1, 2020

Huntington’s Alters Brain Development Before Birth, Study Shows

News

Huntington’s disease alters nerve cell development in the cortex — a brain region largely affected in people with the condition — before birth, a study has found. “Huntington’s definitely ... Read more

August 18, 2020August 18, 2020

Antidopaminergic Meds Ease Chorea But May Worsen Cognition, Study Finds

News

Antidopaminergic medications are associated with lesser chorea and irritability in people with Huntington’s disease, but they may worsen their cognitive skills, data from the largest observational study of the disease show. Future, ... Read more

April 21, 2020August 25, 2020

Vaccinex’s Pepinemab Halts Brain Shrinkage, Eases Symptoms in Early Huntington’s Patients, Results Shows

News

Vaccinex’s experimental therapy pepinemab (VX15/2503) improves brain metabolism, halts its atrophy, and eases motor and cognitive symptoms in people with late prodromal (before clinical diagnosis) and early Huntington’s disease, according to ... Read more

December 5, 2019December 5, 2019

Early Study Identifies 3 Small Molecules That Target Root Cause of Huntington’s

News

Researchers have identified three new small molecules that significantly reduce the formation of toxic aggregates of mutant huntingtin — the underlying cause of Huntington’s disease — in cells derived ... Read more

November 14, 2019November 14, 2019

Mini Pig Model of Huntington’s May be Advantageous in Preclinical Trials, Researchers Say

News

The mini pig model of Huntington’s disease not only has a similar brain anatomy to humans, but also shows the slow and age-dependent neurodegeneration and weight loss that’s characteristic ... Read more

November 13, 2019November 14, 2019

Q-Motor Tool Shows Promise in Detecting Motor Changes in At-risk Children, Study Shows

News

Q-Motor, a promising motor-assessment tool for adults with Huntington’s disease, also provides non-invasive, easy, and sensitive measures to gauge motor function changes in children and adolescents, a study shows. The ... Read more

November 5, 2019November 5, 2019

Microprotein of Mitochondria Helps Regulate Protein Folding and Cell Stress Linked to Disease, Study Finds

News

PIGBOS — a newly discovered mitochondrial microprotein involved in a cellular stress-response mechanism called unfolded protein response (UPR) — might be a treatment target for neurodegenerative diseases like Huntington’s, a ... Read more