Posts by: Marta Figueiredo

Marta Figueiredo

Marta Figueiredo holds a BSc in Biology and a MSc in Evolutionary and Developmental Biology from the University of Lisbon, Portugal. She is currently finishing her PhD in Biomedical Sciences at the University of Lisbon, where she focused her research on the role of several signalling pathways in thymus and parathyroid glands embryonic development.

December 5, 2019December 5, 2019

Early Study Identifies 3 Small Molecules That Target Root Cause of Huntington’s

News

Researchers have identified three new small molecules that significantly reduce the formation of toxic aggregates of mutant huntingtin — the underlying cause of Huntington’s disease — in cells derived ... Read more

November 14, 2019November 14, 2019

Mini Pig Model of Huntington’s May be Advantageous in Preclinical Trials, Researchers Say

News

The mini pig model of Huntington’s disease not only has a similar brain anatomy to humans, but also shows the slow and age-dependent neurodegeneration and weight loss that’s characteristic ... Read more

November 13, 2019November 14, 2019

Q-Motor Tool Shows Promise in Detecting Motor Changes in At-risk Children, Study Shows

News

Q-Motor, a promising motor-assessment tool for adults with Huntington’s disease, also provides non-invasive, easy, and sensitive measures to gauge motor function changes in children and adolescents, a study shows. The ... Read more

November 5, 2019November 5, 2019

Microprotein of Mitochondria Helps Regulate Protein Folding and Cell Stress Linked to Disease, Study Finds

News

PIGBOS — a newly discovered mitochondrial microprotein involved in a cellular stress-response mechanism called unfolded protein response (UPR) — might be a treatment target for neurodegenerative diseases like Huntington’s, a ... Read more

September 17, 2019September 17, 2019

Age of Onset in Huntington’s Linked to Property of CAG Repeat Length in Study

News

Age of onset in Huntington’s disease is associated with a property of the inherited CAG repeat length in the huntingtin (HTT) gene — which determines the probability of further repeat ... Read more

August 20, 2019August 20, 2019

Researchers Find Genetic Overlap Between Psychiatric Disorders and Psychiatric, Cognitive Symptoms in Huntington’s

News

Psychiatric and cognitive symptoms in Huntington’s disease share genetic traits with psychiatric disorders and intelligence, respectively, according to a study. These findings suggest that current treatments used for depression ... Read more

August 8, 2019August 8, 2019

HD Patients Prefer Less Invasive, No-Placebo Gene Therapy Trials, Survey Says

News

Eligible Huntington’s disease patients would likely participate in a gene therapy trial regardless of the study design, but they are more inclined toward those with less invasive interventions and ... Read more

November 29, 2018November 30, 2018

Young People Caring for Huntington’s Disease Parent Worry ‘This Could Be Me’

News

Taking care of parents with Huntington’s disease evokes thoughts of “this could be me” in young caregivers and affects their planning for predictive genetic testing, a study shows. The study, ““This ... Read more

April 3, 2018April 3, 2018

Immunotherapy Candidates Showing Promise as Potential Ways of Treating Huntington’s

News

Potential immunotherapies are showing some positive early results in clinical and preclinical tests, and may offer hope to treat Huntington’s disease, according to a recent review published in the ... Read more

March 24, 2018April 24, 2018

Cannabinoids Seen to Ease Motor Symptoms Like Dystonia in Early-onset Patients in Case Study

News

Cannabinoids can help to treat motor symptoms like dystonia in patients with early-onset Huntington’s disease, a small case study reports. The study, “Cannabinoids for Treatment of Dystonia in Huntington’s ... Read more

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