Author Archives: Marta Figueiredo PhD

Microprotein of Mitochondria Helps Regulate Protein Folding and Cell Stress Linked to Disease, Study Finds

PIGBOS — a newly discovered mitochondrial microprotein involved in a cellular stress-response mechanism called unfolded protein response (UPR) — might be a treatment target for neurodegenerative diseases like Huntington’s, a study suggests. The study, “Regulation of the ER stress response by a mitochondrial microprotein,” was published…

Researchers Find Genetic Overlap Between Psychiatric Disorders and Psychiatric, Cognitive Symptoms in Huntington’s

Psychiatric and cognitive symptoms in Huntington’s disease share genetic traits with psychiatric disorders and intelligence, respectively, according to a study. These findings suggest that current treatments used for depression and psychotic symptoms in the overall population may also be able to treat these symptoms in Huntington’s patients. The…