News

Researcher Hopeful, Sure of Future Cure for Huntington’s Disease

Edward J. Wild, of the National Hospital for Neurology & Neurosurgery, London, has a unique perspective on Huntington’s disease (HD). He believes the currently incurable neurological condition is ideal for certain treatment, based on the clear and universal cause of the disease. Wild elaborated on his conviction in a recent article…

Aging-Related Diseases Might Be Better Understood Via Roundworm Research

Using roundworms to screen chemicals that increase lifespan may improve knowledge on diseases related to aging such as Alzheimer’s, Huntington’s, or cancer, according to initial findings recently revealed at the The Allied Genetics Conference in Orlando, Florida. In a new consortium called the Caenorhabditis Intervention Testing Program (CITP), funded by the National Institute on…

Huntington’s Researchers Identify Novel Compound in Search for Potential Treatment Strategy

Researchers at Massachusetts General Hospital (MGH) report they’ve identified a novel compound that could be a potential therapy strategy for Huntington’s disease, protecting nerve cells from death in both cultured cells and animal models of the disease. The study, “SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in…

Teva’s Therapy for Chorea in Huntington’s Disease, SD-809, Shows Effect in 12-Week Clinical Trial

Results from a Phase 3 clinical trial found that deutetrabenazine (SD-809), an investigational drug developed by Teva Pharmaceutical Industries, improved chorea among Huntington’s disease patients. But the researchers caution that more studies are needed to ascertain the treatment’s long-term effectiveness and safety. Data from the trial showing that the drug improved swallowing…

Huntington’s Research to be Improved by New Mouse Brain Discovery

New data on an uncharted dark spot of the mouse brain map reveals how connections between brain cells form networks responsible for movement and motor learning — tasks that go awry in conditions such as Huntington’s disease. The findings, discovered during a larger comprehensive project by scientists at the University…