The Rutgers’ Human Genetics Institute of New Jersey, home to RUCDR Infinite Biologics — the world’s largest university-based biorepository — announced it has received a five-year grant from the National Institute of Neurological Disorders and Stroke (NINDS). The $6 million funding will allow Rutgers to assume management of the NINDS stem cell repository,…
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October 19, 2015, marks a historical day in the treatment of Huntington’s Disease. At University College London Hospitals, patients afflicted with the degenerative neurological condition that day received an innovative new “gene silencing” drug. There is great hope that this drug will revolutionize the treatment of this destructive disease, for which there is currently…
University of Buffalo researchers have discovered that Huntingtin protein (Htt) is involved in the transport of Rab proteins, which are essential for normal cell function, a discovery that might lead to a greater understanding of the mechanisms behind Huntington’s disease. The research paper entitled “Huntingtin differentially regulates the axonal transport of a sub-set…
In a new study titled “Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression”, published in Molecular Neurodegeneration, researchers have discovered that ethosuximide, a commonly prescribed anti-epileptic drug, has protective and potential therapeutic effects for neurodegenerative diseases, such as Parkinson’s, Alzheimer’s and Huntington’s. To investigate the…
While moving is normal to healthy people, making even the smallest movements may seem a difficult task for those who suffer from movement disorders such as Huntington’s disease. The Houston Methodist Sugar Land Hospital is spreading awareness about these types of conditions and their proper treatment, the importance of seeking professional help…
In a recently published paper in the Brain and Behavior journal entitled “Genetic deletion of the Histone Deacetylase 6 exacerbates selected behavioral deficits in the R6/1 mouse model for Huntington’s disease“, French CNRS researchers in collaboration with institutions from Gottingen in Germany, investigated the…
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Songbirds Could Be Used as Valuable Tool to Study Brain Neurodegeneration, Huntington’s Disease
In a recent paper published in Nature Neuroscience journal entitled “Human mutant huntingtin disrupts vocal learning in transgenic songbirds“, Rockefeller University researchers reported that songbirds could be used as new tool to study Huntington’s disease (HD), providing a more complete understanding of the mechanisms underlying brain neurodegeneration.
In a recent study published in the journal PLOS Currents, a team of researchers from Cambridge in the United Kingdom developed a cheap motor task able to detect motor impairments in both premanifest and manifest Huntington’s disease (HD). According to the researchers the novel task might be a…
The New York Blood Center (NYBC) and the Howard and Abby Milstein Foundation recently announced plans to expand their partnership and joint efforts to further stem cell line technology and application in regenerative medicine. This expansion will also welcome Drs. Peter…
Cloud-based drug design and development company, Cloud Pharmaceuticals, Inc., recently announced it has signed with THERAMetrics holding AG to collaborate on breakthrough treatments for orphan central nervous system (CNS) diseases and other indications. This strategic collaboration has as its primary points of interest Huntington’s disease, amyotrophic lateral sclerosis (ALS), progressive supranuclear palsy…
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