In a recent study, the modification of a specific component of the huntingtin protein reduced neurodegenerative symptoms in an animal model’s brain and offered hope for future therapies that could effectively treat Huntington’s disease in humans. The study, “Serine 421 regulates mutant huntingtin toxicity and clearance in mice,” was published in the…
Researchers from the École Polytechnique Fédérale de Lausanne (EPFL), Switzerland, led by Dr. Matteo Cornaglia, PhD, have developed a new experimental device that can assist scientists in the analysis of molecular pathway studies related to complex human dysfunctions, such as neurodegenerative diseases like Huntington’s (HD). The device is intended for use with the…
A recent study explored the association between gastric mucosa (mucus lining) abnormalities in Huntington’s Disease (HD) and mechanisms in the increased weight loss experienced by HD patients. The study, entitled, “Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington’s Disease,” was published in the journal…
Recently, a group of interdisciplinary researchers from École polytechnique fédérale de Lausanne (EPFL), Switzerland, and the New York University Langone Medical Center, made a discovery that could lead to new treatment options for neurological disorders such as Huntington’s disease (HD). The study, entitled “Cell-Type-Specific Sensorimotor Processing…
Researchers from The Rockefeller University, New York, in collaboration with Columbia University, New York, have recently released results from a study in which they identified the molecular changes that results in the loss of neurons in Parkinson’s disease (PD); a discovery that may have significant implications in discovering…
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