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Novel RNA Diagnostic Tests Monitor Organ Health in Neurodegenerative, Liver Diseases

San Diego-based Molecular Stethoscope, a company that develops blood-based early detection and disease monitoring tests, is partnering with 23 national medical and academic institutions to address some of the most puzzling scientific questions about disease diagnosis and monitoring. The company has developed clinically actionable tests that analyze organ-specific circulating…

Lithium May Help Huntington’s Patients Who Have Suicidal Tendencies, Study Finds

Lithium may be effective to eliminate suicidal symptoms in patients with Huntington’s disease (HD), according to a study titled “Huntington’s disease and suicidal behavior: The importance of lithium treatment,” published in the journal Clinical Neurology and Neurosurgery. Huntington’s disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination…

‘Spotlight on Hope’ to Raise Funds and Awareness for Neurological Disorders, Including Huntington’s

The Colorado Neurological Institute (CNI), a nonprofit organization promoting research, education, and patient services for those with neurological conditions, announced it will host its “Spotlight on Hope” fundraising gala on April 15 at the Ritz-Carlton in Denver. The gala is both a chance for the public to better understand brain cancers, attacks…

Huntington’s Disease Researcher at University of Wyoming Granted Patent for Novel Treatment Approach

The University of Wyoming was recently granted a patent for a therapeutic technique that targets the mutant protein causing Huntington’s disease, and may lead to a new way of treating people with Huntington’s and other neurodegenerative diseases. Its inventor, Jonathan Fox, is a veterinary pathologist and associate professor in the Department of Veterinary Sciences. Dr.

Researchers Push for Therapeutic Targets to Prevent Synapse Loss in Huntington’s, Alzheimer’s Diseases

Scientists at Boston Children’s Hospital have revealed the cellular and biological mechanisms involved in synapse loss in Alzheimer’s disease. By blocking certain agents involved in this process, scientists could halt synaptic loss, a discovery with therapeutic potential not only for Alzheimer’s, but also other diseases with loss of neuronal connections, including Huntington’s disease. The…

Gene Therapy Approach Reported to Block Mutant Huntington’s Gene in Preclinical Studies

uniQure recently published results from preclinical studies of its gene therapy program, AMT-130, indicating that a one-time administration of AAV5-delivered therapy into the central nervous system can block the mutant HTT gene that causes Huntington’s disease (HD). These findings, in the article “Design, Characterization, and Lead Selection of Therapeutic miRNAs…