In Huntington’s Disease, Calcium Overload Leads to Mitochondrial Dysfunction and Cell Death
Researchers at Philadelphia’s Thomas Jefferson University investigated the physiological and pathological role of MICU1 (Mitochondrial Calcium Uptake 1), a protein that controls calcium by the mitochondria, a process involved in cell survival. Results suggest that strengthening this protein’s function and inhibiting mitochondrial calcium uptake could be a novel therapeutic approach…