The Colorado Neurological Institute (CNI), a nonprofit organization promoting research, education, and patient services for those with neurological conditions, announced it will host its “Spotlight on Hope” fundraising gala on April 15 at the Ritz-Carlton in Denver. The gala is both a chance for the public to better understand brain cancers, attacks…
The University of Wyoming was recently granted a patent for a therapeutic technique that targets the mutant protein causing Huntington’s disease, and may lead to a new way of treating people with Huntington’s and other neurodegenerative diseases. Its inventor, Jonathan Fox, is a veterinary pathologist and associate professor in the Department of Veterinary Sciences. Dr.
Scientists at Boston Children’s Hospital have revealed the cellular and biological mechanisms involved in synapse loss in Alzheimer’s disease. By blocking certain agents involved in this process, scientists could halt synaptic loss, a discovery with therapeutic potential not only for Alzheimer’s, but also other diseases with loss of neuronal connections, including Huntington’s disease. The…
Researchers discovered that frequently used fungicides – chemicals used commercially to get rid of fungi in crops – cause the same kind of changes in gene expression as scientists report are present in patients with neurodegenerative diseases, such as Huntington’s and Alzheimer’s diseases, as well as autism. The study, “…
uniQure recently published results from preclinical studies of its gene therapy program, AMT-130, indicating that a one-time administration of AAV5-delivered therapy into the central nervous system can block the mutant HTT gene that causes Huntington’s disease (HD). These findings, in the article “Design, Characterization, and Lead Selection of Therapeutic miRNAs…
Two nonprofit groups advocating for those with Huntington’s disease (HD), HD Reach and the North Carolina Chapter of the Huntington’s Disease Society of America (HDSA-NC), have announced a second daylong educational event for people with HD, their families, and caregivers. This year’s NC HD “Hope for Health, Hope for Life” will be at held…
University of California at Davis researchers have, for the first time, successfully tested human stem cells (MSCs) as a delivery system for a key protein growth factor in mouse models of Huntington’s disease (HD), an important step for the development of novel therapies. The research article, “Human Mesenchymal Stem Cells…
The English Parliament recently listened to a young scientist, Emma Yhnell, 25, explain her research into the potential of computer games to “train the brain” of Huntington’s disease (HD) patients. The research associate from Cardiff University in Wales attended Parliament on March 7 to present her novel approach to a range of politicians and…
Researchers at Philadelphia’s Thomas Jefferson University investigated the physiological and pathological role of MICU1 (Mitochondrial Calcium Uptake 1), a protein that controls calcium by the mitochondria, a process involved in cell survival. Results suggest that strengthening this protein’s function and inhibiting mitochondrial calcium uptake could be a novel therapeutic approach…
New Huntington’s research sheds light on the link between the effects of the disease’s underlying mutation on brain structure and function, and consequent behavior anomalies. Studying the gene mutation’s expression in a precise brain area of songbirds, scientists observed how the mutation affects specific neurons and changes behavior, findings that could lead to the…
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