Being physically active is significantly associated with a delayed age of the onset of Huntington’s disease and spending more time watching television is significantly linked to an earlier age of onset. These are the findings of a study that analyzed genetic variants linked with different levels of physical activity…

Beyond genetic factors, the onset of Huntington’s disease later in life was related to being in a stable partnership, living in large cities, and having lower education levels, a large-scale analysis suggests. In comparison, a younger age at disease onset was associated with suicidal behavior and the use of…

The length of CAG repeats within the huntingtin (HTT) gene tends to increase as people with Huntington’s disease get older and is directly correlated with poor clinical outcomes, a study has found. The study, “A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and…

Age of onset in Huntington’s disease is associated with a property of the inherited CAG repeat length in the huntingtin (HTT) gene — which determines the probability of further repeat expansions in nerve cells — rather than with the toxicity of the protein it produces, a study suggests. Along…

One of the more tragic aspects of Huntington’s disease (HD) is how the symptoms can begin to take control of a person in their prime adult years. There’s no cure or effective treatment available to us yet, so it’s like those of us who are gene positive for…

A deficiency in energy metabolism in the cells of patients with Huntington’s disease can partly explain the variation in age of onset among individuals, a study shows. The study, “Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset,” was published in the journal…

Arterial hypertension was linked to a later age of disease onset in Huntington’s patients in a study in Europe. The study, “Does arterial hypertension influence the onset of Huntington’s disease?” was published in the journal PLOS One. Previous research has shown an association between the age of onset…