Behavioral changes due to early onset Huntington’s disease and problems with school, and social and family life are common, particularly among pediatric patients, according to a case series study in Germany. Socio-medical problems in these children were associated both with their own disease, and with the additional burden of parents…
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Antidopaminergic medications are associated with lesser chorea and irritability in people with Huntington’s disease, but they may worsen their cognitive skills, data from the largest observational study of the disease show. Future, prospective studies are needed to confirm these findings, and to determine whether treatments to lower dopamine levels indeed…
Teva Pharmaceuticals’ Austedo (deutetrabenazine tablets) has been approved by China’s National Medical Products Administration (NMPA) for treating chorea associated with Huntington’s disease and tardive dyskinesia…
Rexulti (brexpiprazole), an antipsychotic medicine approved for schizophrenia and in some cases depression, eases motor and psychiatric symptoms of Huntington’s disease, according to a case study. The study, “Effectiveness of Brexpiprazole in the Treatment in a Patient with Huntington’s Disease,” was published in the…
There may be no cure yet for Huntington’s disease, but patients — and their families — can still do plenty to extend their life expectancy through proper diet, exercise, and emotional support. That’s the message Norway’s Astri Arnesen wants to share with the world. Arnesen, president of the European…
Huntington’s disease is a progressive neurodegenerative disorder, caused by inheritable mutations in the huntingtin (HTT) gene. The mutation produces a toxic form of the HTT protein that aggregates in and ultimately kills nerve cells. This results in various symptoms, including movement, cognitive, and psychiatric problems. There is…
Zyprexa (olanzapine) is an antipsychotic medication, manufactured by Eli Lilly, and approved by the U.S. Food and Drug Administration (FDA) to treat schizophrenia, depression, and bipolar disorder. It may be prescribed to treat some motor and behavioral symptoms of Huntington’s disease, sometimes in…
Delusions and hallucinations are among the psychiatric symptoms of Huntington’s disease, occurring in an estimated 3-11% of patients. These symptoms are also collectively referred to as psychosis. What are delusions and hallucinations? Delusions Delusions can be defined as false beliefs. No arguments or evidence can convince patients with…
Huntington’s disease is a hereditary neurodegenerative disorder characterized by an imbalance in the levels of dopamine in the brain. Dopamine is a neurotransmitter, or signaling molecule, that plays a vital role in abilities that include movement. Unusually high levels of dopamine are thought to cause chorea (involuntary jerking or…
Huntington’s disease is an incurable genetic condition, marked by uncontrollable and jerky movements known as chorea, as well as cognitive, behavioral, and emotional changes. This disease and its symptoms typically begin in adulthood and worsen over time, but can be more manageable with certain adjustments and therapy approaches.