A research report discusses the use of six versions of a new type of molecule, known as xyloketal B, for the treatment of Huntington’s disease. Scientists tested the six possible drugs in a worm model of Huntington’s disease, Caenorhabditis elegans. Results of the study, “Xyloketal-derived small molecules show protective effect…
A geneticist and neuropsychologist whose research led to the identification of the gene involved in Huntington’s disease (HD) has been named the inaugural recipient of the Hermann J. Muller Award for Contributions to Our Understanding of Genes and Society, a new honor by Indiana University Bloomington. Nancy…
A recent study published in the journal Neuron by University of California at Irvine researchers revealed that the protein PIAS1 regulates the accumulation of a mutant protein in Huntington’s disease, and its expression associates with disease pathogenesis in a mouse model of the disease. The study, “PIAS1 Regulates Mutant Huntingtin Accumulation…
Cambridge, England-based light therapy specialist Lumie will supply 24 of its most powerful light boxes, called Lumie Brazil, for use in a Huntington’s disease research study at the Cambridge School of Clinical Medicine’s Neurology Unit. The Lumies are being donated to…
San Diego-based Molecular Stethoscope, a company that develops blood-based early detection and disease monitoring tests, is partnering with 23 national medical and academic institutions to address some of the most puzzling scientific questions about disease diagnosis and monitoring. The company has developed clinically actionable tests that analyze organ-specific circulating…
Lithium may be effective to eliminate suicidal symptoms in patients with Huntington’s disease (HD), according to a study titled “Huntington’s disease and suicidal behavior: The importance of lithium treatment,” published in the journal Clinical Neurology and Neurosurgery. Huntington’s disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination…
The Colorado Neurological Institute (CNI), a nonprofit organization promoting research, education, and patient services for those with neurological conditions, announced it will host its “Spotlight on Hope” fundraising gala on April 15 at the Ritz-Carlton in Denver. The gala is both a chance for the public to better understand brain cancers, attacks…
The University of Wyoming was recently granted a patent for a therapeutic technique that targets the mutant protein causing Huntington’s disease, and may lead to a new way of treating people with Huntington’s and other neurodegenerative diseases. Its inventor, Jonathan Fox, is a veterinary pathologist and associate professor in the Department of Veterinary Sciences. Dr.
Scientists at Boston Children’s Hospital have revealed the cellular and biological mechanisms involved in synapse loss in Alzheimer’s disease. By blocking certain agents involved in this process, scientists could halt synaptic loss, a discovery with therapeutic potential not only for Alzheimer’s, but also other diseases with loss of neuronal connections, including Huntington’s disease. The…
Researchers discovered that frequently used fungicides – chemicals used commercially to get rid of fungi in crops – cause the same kind of changes in gene expression as scientists report are present in patients with neurodegenerative diseases, such as Huntington’s and Alzheimer’s diseases, as well as autism. The study, “…
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