News

FDA Clears Genetically Engineered Mini Pig Model For Use in Research And Drug Development

Exemplar Genetics announced that the U.S. Food & Drug Administration (FDA) has cleared its low-density lipoprotein receptor (LDLR) mini pig for use in scientific studies. In the future, this type of model could become an invaluable addition to study diseases such as Huntington’s disease, as mouse models have proven insufficient at optimally translating preclinical research…

Cutting-edge Research into Huntington’s, Alzheimer’s, Other Diseases to Be Focus of New UCSF Weill Institute for Neurosciences

The Weill Family Foundation and Joan and Sanford I. “Sandy” Weill have donated $185,000,000 to the University of California, San Francisco, to establish the UCSF Weill Institute for Neurosciences in an effort to expedite the development of new therapies for brain and nervous system diseases, including Huntington’s disease and Alzheimer’s…

Researchers Decrease Accumulation of Damaging Huntington’s Disease Protein Using New Method in Mice

A recent study published in the journal Neuron by University of California at Irvine researchers revealed that the protein PIAS1 regulates the accumulation of a mutant protein in Huntington’s disease, and its expression associates with disease pathogenesis in a mouse model of the disease. The study, “PIAS1 Regulates Mutant Huntingtin Accumulation…

Novel RNA Diagnostic Tests Monitor Organ Health in Neurodegenerative, Liver Diseases

San Diego-based Molecular Stethoscope, a company that develops blood-based early detection and disease monitoring tests, is partnering with 23 national medical and academic institutions to address some of the most puzzling scientific questions about disease diagnosis and monitoring. The company has developed clinically actionable tests that analyze organ-specific circulating…

Lithium May Help Huntington’s Patients Who Have Suicidal Tendencies, Study Finds

Lithium may be effective to eliminate suicidal symptoms in patients with Huntington’s disease (HD), according to a study titled “Huntington’s disease and suicidal behavior: The importance of lithium treatment,” published in the journal Clinical Neurology and Neurosurgery. Huntington’s disease (HD) is a neurodegenerative genetic disorder that affects muscle coordination…

‘Spotlight on Hope’ to Raise Funds and Awareness for Neurological Disorders, Including Huntington’s

The Colorado Neurological Institute (CNI), a nonprofit organization promoting research, education, and patient services for those with neurological conditions, announced it will host its “Spotlight on Hope” fundraising gala on April 15 at the Ritz-Carlton in Denver. The gala is both a chance for the public to better understand brain cancers, attacks…