Patricia Inácio, PhD, science writer —

Patricia holds her PhD in cell biology from the University Nova de Lisboa, Portugal, and has served as an author on several research projects and fellowships, as well as major grant applications for European agencies. She also served as a PhD student research assistant in the Department of Microbiology & Immunology, Columbia University, New York, for which she was awarded a Luso-American Development Foundation (FLAD) fellowship.

Articles by Patricia Inácio

Rilmenidine Well-Tolerated in HD Patients, but More Studies Needed, Researchers Say

Researchers have found that rilmenidine, a blood pressure medicine, was relatively safe and well-tolerated by Huntington’s disease (HD) patients in a small study. However, its effectiveness in treating the disease remains unknown and warrants further investigation. The study, “An open-label study to assess the feasibility and tolerability of rilmenidine for…

Researchers Identify Mechanism to Prevent Toxic Accumulation of Proteins in Mitochondria

Researchers have identified an elaborate protein quality control system that prevents toxic accumulation of faulty proteins inside mitochondria, a phenomenon that underlies many neurodegenerative diseases, including Huntington’s disease. The study, ”Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis,” was published in the journal Cell.

Huntington’s Causes Hearing Problems, Study with a Small Sample Size Suggests

Huntington’s disease causes hearing problems, a study with a small sample size suggests. The research, “Auditory dysfunction in patients with Huntington’s disease,“ was published in Clinical Neurophysiology. A severe, inherited neurodegenerative disease, Huntington’s is characterized by movement problems, cognitive deterioration and behavioral disorders. Many people with other neurodegenerative…

Using Gene Editing to Suppress Activity of Protein Mutations Could Be Way to Treat Huntington’s, Study Reports

Researchers used gene editing to suppress the activity of protein mutations in the brains of mice with  Huntington’s disease. Suppressing the huntingtin protein alleviated early signs of the disease and reduced the mice’s movement problems, the study reported. The research, “CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of…