June 27, 2017June 27, 2017
Ionis Completes Patient Enrollment in Phase 1/2a Trial of Ionis-HTTRx for Huntington’s Disease
News
Ionis Pharmaceuticals has completed enrollment of the Phase 1/2a study evaluating the safety, tolerability, properties and movement within the ... Read more
June 22, 2017June 22, 2017
Researchers Identify Variant in MSH3 Gene Related to Huntington’s Progression
News
Researchers have identified a variant in the gene MSH3 that is linked with Huntington’s disease (HD) progression. The study, ... Read more
June 20, 2017
Inhibiting Enzyme Slows Huntington’s Progression in Mice and Lengthens Their Lives, Study Reports
News
Inhibiting the activity of an enzyme preserved the movement capabilities of mice with Huntington’s, slowed the progression of the ... Read more
June 15, 2017June 15, 2017
Low Pyk2 Protein Levels May Contribute to Memory Deficits in Huntington’s Disease, Study Shows
News
Low levels of a protein called Pyk2 may be associated with the development of Huntington’s disease, according to a ... Read more
June 13, 2017
Researchers Propose NfL as New Blood Marker of Huntington’s Disease Onset, Progression
News
A factor called neurofilament light (NfL) may act as a biomarker of progression in Huntington’s disease, as blood levels ... Read more
June 8, 2017
Cell Transport ‘Traffic Jam’ Caused by Mutated Protein, Researchers Discover
News
A mutated form of the huntingtin (mHTT) protein has been acknowledged as the cause of Huntington’s disease, but researchers ... Read more
June 6, 2017
Voyager Selects Gene Therapy Candidate for Huntington’s Clinical Trials
News
Voyager Therapeutics has a new candidate for the treatment of Huntington’s disease. The selected gene therapy is called VY-HTT01 and aims ... Read more
June 1, 2017June 1, 2017
Researchers Identify a Key Link Between the Brain’s Immune Cells and Neurodegenerative Disorders
News
Researchers at the University of California and the Salk Institute for Biological Studies have identified the mechanisms that make ... Read more
May 30, 2017
Researchers Find Common Disease Processes in Huntington’s, Alzheimer’s and Parkinson’s
News
Abnormal proteins found in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s seem to rely on the same mechanism ... Read more
May 25, 2017May 25, 2017
Neuroprotective Pathway May Be Key to Understanding Huntington’s Progression
News
A team of researchers has discovered new insights into cell processes that have gone awry in Huntingon’s disease (HD) ... Read more
May 23, 2017
University of Sussex Researchers Receive $3.37 Million to Develop Huntington’s Treatments
News
Researchers at the Sussex Drug Discovery Centre in Brighton, England, have received a £3 million grant from Britain’s non-profit Wellcome Trust to develop ... Read more
May 18, 2017
Researchers Discover Why Defects Form in Blood Brain Barrier of Huntington’s Patients
News
Researchers have discovered why Huntington’s disease (HD) patients have defects in the blood-brain barrier that contribute to the symptoms ... Read more

Ionis Completes Patient Enrollment in Phase 1/2a Trial of Ionis-HTTRx for Huntington’s Disease

Ionis Pharmaceuticals has completed enrollment of the Phase 1/2a study evaluating the safety, tolerability, properties and movement within the body of Ionis-HTTRx in patients with Huntington’s disease (HD). Patients ... Read more

June 22, 2017June 22, 2017

Researchers Identify Variant in MSH3 Gene Related to Huntington’s Progression

News

Researchers have identified a variant in the gene MSH3 that is linked with Huntington’s disease (HD) progression. The study, “Identification of genetic variants associated with Huntington’s disease progression: a ... Read more

June 20, 2017

Inhibiting Enzyme Slows Huntington’s Progression in Mice and Lengthens Their Lives, Study Reports

News

Inhibiting the activity of an enzyme preserved the movement capabilities of mice with Huntington’s, slowed the progression of the disease and extended the animals’ lives, according to a study. ... Read more

June 15, 2017June 15, 2017

Low Pyk2 Protein Levels May Contribute to Memory Deficits in Huntington’s Disease, Study Shows

News

Low levels of a protein called Pyk2 may be associated with the development of Huntington’s disease, according to a new study. Researchers found that normalizing its levels in the ... Read more

June 13, 2017

Researchers Propose NfL as New Blood Marker of Huntington’s Disease Onset, Progression

News

A factor called neurofilament light (NfL) may act as a biomarker of progression in Huntington’s disease, as blood levels of the molecule increase with more severe neurodegeneration. However, the ... Read more

June 8, 2017

Cell Transport ‘Traffic Jam’ Caused by Mutated Protein, Researchers Discover

News

A mutated form of the huntingtin (mHTT) protein has been acknowledged as the cause of Huntington’s disease, but researchers have not been fully clear about how it disrupts the ... Read more

June 6, 2017

Voyager Selects Gene Therapy Candidate for Huntington’s Clinical Trials

News

Voyager Therapeutics has a new candidate for the treatment of Huntington’s disease. The selected gene therapy is called VY-HTT01 and aims to prevent the production of protein from the mutant huntingtin ... Read more

June 1, 2017June 1, 2017

Researchers Identify a Key Link Between the Brain’s Immune Cells and Neurodegenerative Disorders

News

Researchers at the University of California and the Salk Institute for Biological Studies have identified the mechanisms that make the brain’s immune cells different from all other immune cells A ... Read more

May 30, 2017

Researchers Find Common Disease Processes in Huntington’s, Alzheimer’s and Parkinson’s

News

Abnormal proteins found in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s seem to rely on the same mechanism to spread within the brain and disrupt its normal functions, ... Read more

May 25, 2017May 25, 2017

Neuroprotective Pathway May Be Key to Understanding Huntington’s Progression

News

A team of researchers has discovered new insights into cell processes that have gone awry in Huntingon’s disease (HD) patients. This discovery could point scientists toward a potential method ... Read more

May 23, 2017

University of Sussex Researchers Receive $3.37 Million to Develop Huntington’s Treatments

News

Researchers at the Sussex Drug Discovery Centre in Brighton, England, have received a £3 million grant from Britain’s non-profit Wellcome Trust to develop Huntington’s disease treatments. The team will team up with other ... Read more

May 18, 2017

Researchers Discover Why Defects Form in Blood Brain Barrier of Huntington’s Patients

News

Researchers have discovered why Huntington’s disease (HD) patients have defects in the blood-brain barrier that contribute to the symptoms of this neurological disorder. Their study, “Huntington’s Disease iPSC-Derived Brain ... Read more