News

September 21, 2017September 21, 2017

Huntington’s Patients Would Benefit from More Hospice Involvement, Researchers Argue

Less is known about the late stages of Huntington’s disease than about its earlier stages, particularly concerning patients enrolled in hospice care. Researchers studying this patient group recently concluded ... Read more

September 19, 2017

Webinar to Look at Laughter and Humor as Ways to Help Deal with Huntington’s

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GeneFo will offer a free webinar on how adding humor to Huntington’s patients’ lives can help improve their symptom management, emotional wellbeing, ability to cope with adversity, and social and work ... Read more

September 5, 2017September 5, 2017

Huntington’s Causes Hearing Problems, Study with a Small Sample Size Suggests

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Huntington’s disease causes hearing problems, a study with a small sample size suggests. The research, “Auditory dysfunction in patients with Huntington’s disease,“ was published in Clinical Neurophysiology. A severe, ... Read more

August 31, 2017August 31, 2017

Researchers Create New Cell Model to Study Functions of Mutant Protein in Huntington’s

Huntington's Disease News, News

Researchers generated the first human line of Huntington’s disease induced pluripotent stem cells (iPSCs) that do not express the dysfunctional protein underlying the condition. The cells represent a potential ... Read more

August 29, 2017

AC Immune Identifies Antibodies Against the Alpha-Synuclein, TDP-43 Proteins Linked to Huntington’s

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AC Immune has identified antibodies that target the alpha-synuclein and TDP-43 proteins associated with neurodegenerative diseases such as Huntington’s. The discovery could be used to develop treatments for such diseases, the ... Read more

August 24, 2017August 24, 2017

New CRISPR-Cas9 Technique Corrects Defects Linked to Huntington’s, UCSD Study Suggests

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A new version of the CRISPR-Cas9 gene editing technique designed to target RNA molecules can fix the underlying cause of Huntington’s disease and similar disorders, say researchers at the ... Read more

August 22, 2017August 22, 2017

Identification of Huntington’s Disease Progression Gene Raises Hope of New Treatments

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Researchers in England and Wales have identified a gene linked to disease progression in Huntington’s disease, shedding new light on the poorly understood mechanisms that cause the disorder. Although ... Read more

August 17, 2017

How Mutant Protein Drives Cellular Toxicity in Huntington’s Revealed in Study

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Aggregates of mutant huntingtin protein have been associated with cellular toxicity in Huntington’s disease. Now researchers have discovered that isolated forms of mutated huntingtin are actually responsible for major molecular changes ... Read more

August 15, 2017August 15, 2017

UniQure Plans Tests That Could Lead to Clinical Trial of AMT-130 Gene Therapy for Huntington’s

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Dutch pharmaceutical company uniQure says it plans to conduct preclinical studies leading to clinical testing of a gene therapy in patients with Huntington’s disease. The company is developing AMT-130, an experimental therapy ... Read more

August 1, 2017

Using Gene Editing to Suppress Activity of Protein Mutations Could Be Way to Treat Huntington’s, Study Reports

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Researchers used gene editing to suppress the activity of protein mutations in the brains of mice with Huntington’s disease. Suppressing the huntingtin protein alleviated early signs of the disease ... Read more