Columns

My Wife Is Taking the Right Steps to Manage Her ADHD

Recently, my wife, Jill, underwent testing for attention-deficit hyperactivity disorder (ADHD) and discovered that she has it. This was not shocking news, as readers of this column know. One of the questions her nurse practitioner asked was, “How did you live for 44 years without being diagnosed with…

Words of Encouragement Bond Us to Other HD Families

In a recent column, I wrote about the high emotional cost my wife, Jill, and I face by writing a weekly column about her journey being gene-positive for Huntington’s disease (HD). It doesn’t help that our daughter is also gene-positive. Jill wondered if our weekly column was…

Huntington’s Protein Clumps Form Distinct Structures in Nerve Cells

Clumps of protein resulting from HTT mutations, the underlying cause of Huntington’s disease, form distinct structures in different parts of the cell, according to detailed imaging analysis. The findings suggest these clumps form by different mechanisms and may require different therapeutic strategies to block their formation and toxicity that…