The activity of focal adhesion kinase (FAK), an enzyme known to play an essential role in nerve cell function, is…
Articles by Steve Bryson, PhD
Beyond genetic factors, the onset of Huntington’s disease later in life was related to being in a stable partnership,…
A 56-year-old man with undiagnosed late-onset Huntington’s disease presented with Parkinson’s disease-like symptoms, including bradykinesia, or slowness of movement,…
Activating the JAK2-STAT3 pathway in astrocyte cells reduced multiple hallmark features of Huntington’s disease — including the toxic clumping…
Clumps of protein resulting from HTT mutations, the underlying cause of Huntington’s disease, form distinct structures in different parts…
The perception of time is impaired in people with symptomatic Huntington’s disease in its early stages — but not…
Frequent bladder, bowel, and sexual problems were reported by people with Huntington’s disease, a study reveals. Recommended…
No significant safety concerns were found in the first four patients participating in a Phase 1/2 trial assessing…
Based on MRI scans, Huntington’s disease patients with major cognitive impairments have reduced gray matter volume and…
A single injection of the protein CDNF — cerebral dopamine neurotrophic factor — into the brains of rats with…