Posts by: Alice Melão

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Mutations linked to Huntington’s disease cause more extensive remodeling of functional connectivity in various regions of the brain than previously thought, affecting patients’ motor and cognitive skills, research looking ... Read more

March 20, 2018March 20, 2018

New Version of Genome Editing System Holds Potential to Treat Huntington’s

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A modified version of the genome-editing CRISPR-Cas9 system may prevent the production of faulty huntingtin protein, moving closer to treatment for Huntington’s disease. The study, “Precise Excision of the ... Read more

February 27, 2018February 27, 2018

Huntington’s Patients’ Skin Cells Transformed Into Nerve Cells That Mimic Disease Symptoms

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Nerve cells that mimic the molecular features of Huntington’s disease have been created from patients’ skin cells, researchers said. The study, “Striatal neurons directly converted from Huntington’s disease patient ... Read more

January 16, 2018January 16, 2018

Strict Meal Schedule May Benefit Huntington’s Patients, UCLA Mouse Study Suggests

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Keeping a strict eating schedule may help improve the quality of life of patients with Huntington’s disease and other neurodegenerative disorders, a mouse study suggests. The study, “Time restricted ... Read more

January 11, 2018January 11, 2018

MMJ Files US Patent for Cannabinoid-based Treatment for Huntington’s and MS

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MMJ BioScience has filed a patent invention with the U.S. Patent and Trademark Office for its part-cannabinoid treatment for patients with cannabinoid-responsive diseases, including Huntington’s disease and multiple sclerosis. According ... Read more

December 14, 2017

Researchers Review Role of Manganese in Huntington’s Disease Development

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The chemical compound manganese (Mn) has been reported to take part in the underlying mechanism of Alzheimer’s disease. However, little is known about its involvement in the development of ... Read more

December 7, 2017December 7, 2017

Scientists Control Stem Cells’ Change to Neurons, a Potentially Valuable Tool for Huntington’s

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Embryonic stem cells have been seen as a potential therapeutic strategy for several diseases. However, the manipulation of these cells has been a challenge for scientists due to their ... Read more

December 5, 2017December 5, 2017

Activity and Levels of Enzyme Aco2 May Be Biomarker of Huntington’s Progression, Early Study Reports

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A poorly active enzyme called aconitase 2 (Aco2), found at low levels in cells, can be a marker of the mitochondrial dysfunction linked to Huntington’s disease and its progression, ... Read more

October 26, 2017October 26, 2017

Plant Study Reveals Mechanism That May Explain Protein Folding in Human Disease

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A Spanish study investigating the functioning of chloroplasts — the nutrient-producing “factory” of plants — has revealed a new mechanism that helps understand how a cell controls and regulates ... Read more

October 3, 2017October 3, 2017

Measuring PFS Outcome Might Help Researchers Evaluate Huntington’s Progression, Study Suggests

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Identifying Huntington’s disease progression can be a challenge in clinical trials. Now, an international team of researchers proposes in an article published in JAMA Neurology the use of a new ... Read more

Posts by: Alice Melão

Alice Melão

HTT Mutations Seen to Cause Extensive Brain Remodeling, Affecting Motor and Cognitive Skills

New Version of Genome Editing System Holds Potential to Treat Huntington’s

Huntington’s Patients’ Skin Cells Transformed Into Nerve Cells That Mimic Disease Symptoms

Strict Meal Schedule May Benefit Huntington’s Patients, UCLA Mouse Study Suggests

MMJ Files US Patent for Cannabinoid-based Treatment for Huntington’s and MS

Researchers Review Role of Manganese in Huntington’s Disease Development

Scientists Control Stem Cells’ Change to Neurons, a Potentially Valuable Tool for Huntington’s

Activity and Levels of Enzyme Aco2 May Be Biomarker of Huntington’s Progression, Early Study Reports

Plant Study Reveals Mechanism That May Explain Protein Folding in Human Disease

Measuring PFS Outcome Might Help Researchers Evaluate Huntington’s Progression, Study Suggests

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