Blocking immune system proteins that are part of the body’s complement cascade — which helps the immune system to fight infection — was found to protect nerve cell connections between two brain regions known to be affected in Huntington’s disease in a mouse model of the rare disorder. It…
Blood samples may be crucial in tracking brain changes that occur in people with Huntington’s disease, a new study finds. Researchers also report that Huntington’s and Alzheimer’s patients have certain inflammatory mechanisms in common, suggesting a potential for shared therapeutic approaches. The study, “Huntington’s disease blood and brain show a common gene expression pattern and share an…
Inflammatory processes in both the brain and the rest of the body are likely an integral part of Huntington’s disease, according to a review of published data on the topic. The report, “Neuroimmunology of Huntington’s Disease: Revisiting Evidence from Human Studies,” published in the journal Mediators…
Despite efforts to develop therapies to treat Huntington’s disease (HD), so far no treatment has been shown to effectively stop, slow, or reverse disease progression. Now, an animal study suggests that treating mice with the experimental drug laquinimod can improve some neuropathologic and behavioral features of Huntington’s. The study, titled “Laquinimod…
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