Levels of proteins derived from prodynorphin (PDYN) — ultimately used during cell-to-cell signaling in the brain — are decreased in the fluid surrounding the brains of people with Huntington’s disease (HD), a new small study suggests. These findings indicate that PDYN-derived proteins could be used as specific biological…
Levels of a protein called neurofilament light (NFL) could be a valuable biomarker for tracking Huntington’s disease progression, according to a study. The research, “Tau Or Neurofilament Light—Which Is The More Suitable Biomarker For Huntington’s Disease?,” was published in the journal PLoS One. Huntington’s is caused by an…
Tapping into the cerebrospinal fluid (CSF) of patients with Huntington’s disease may give insights on disease onset, diminished functional ability and potential therapeutic agents for treatment. A recent study investigated whether huntingtin (HTT) protein could be detected in CSF, and the research team behind the investigation created an assay with…
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