Huntington’s Disease News

March 10, 2020March 10, 2020

Pediatric Rare Disease Therapies Increase, But Most Repurposed, Study Finds

The number of treatments for children with rare diseases has grown over the past decade, according to a new study. However, despite the increase, nearly 7,000 rare diseases are still ... Read more

June 21, 2018June 21, 2018

New Huntingtin Protein Strategy Significantly Improves Symptoms Over Time, Study Finds

Huntington's Disease News, News

A new therapeutic strategy based on a small part of the huntingtin protein — which in a mutated form is responsible for Huntington’s disease — shows potential to regulate ... Read more

August 31, 2017August 31, 2017

Researchers Create New Cell Model to Study Functions of Mutant Protein in Huntington’s

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Researchers generated the first human line of Huntington’s disease induced pluripotent stem cells (iPSCs) that do not express the dysfunctional protein underlying the condition. The cells represent a potential ... Read more

November 20, 2015May 14, 2016

Huntington’s Gene Produces Cocktail of Mutant RAN Proteins

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A group of researchers from the University of Florida Health have discovered new information about Huntington’s disease, namely that the gene causing this severe disorder causes an unforeseen accumulation of ... Read more

November 18, 2015November 18, 2015

Potential Treatment Prototype for Taupathies and Neurodegenerative Brain Diseases Under Development

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Researchers at the German Center for Neurodegenerative Diseases (DZNE) in Bonn have tested a new substance that may lead to a prototype for the development of drugs to treat Alzheimer’s ... Read more

November 4, 2015November 4, 2015

In Huntington’s, Dysfunctions of Neuronal Pathways Are Broad and Shared

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In a recent review entitled “Neuronal response in Alzheimer’s and Parkinson’s disease: the effect of toxic proteins on intracellular pathways,” published in the BMC Neuroscience journal, researchers discuss neuronal ... Read more

September 18, 2015September 18, 2015

Bioinformatics Unlocks Mechanisms of Disease Progression

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Bioinformatics, a field that enables powerful analysis of large amounts of data, is being applied to Huntington’s disease to find potential candidate molecules that play a role in pathogenesis. ... Read more

September 7, 2015September 8, 2015

Highly Sensitive Assay for mHTT Predicts Huntington’s Disease

Huntington's Disease News, News

Tapping into the cerebrospinal fluid (CSF) of patients with Huntington’s disease may give insights on disease onset, diminished functional ability and potential therapeutic agents for treatment. A recent study ... Read more

August 31, 2015August 31, 2015

Huntington Disease-Afflicted Families May Share Common Ancestors

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Could patients with Huntington’s disease (HD) who are of European ancestry be related by a distant individual? Perhaps, according to a study from the Center for Human Genetic Research ... Read more