Changes in the shape of a brain region called the neostriatum — involved in motor and cognitive control — are…
Articles by Joana Carvalho, PhD
People with Huntington’s disease may have two different symptom profiles, a cognitive-motor and a psychiatric profile, associated with…
Mutant huntingtin, the protein involved in Huntington’s disease, travels from one neuron to another using a network of tunnels…
Mild genetic or environmental changes that upset the circadian clock (our internal sleep-wake cycle) may work to diminish the toxicity…
Patients at advanced stages of Huntington’s disease have marked difficulties in controlling vehicles in a driving simulator compared…
Researchers narrowing in on early neuronal functioning stages of development, well before Huntington’s disease symptoms appear, believe they have found a…
Time perception is impaired in patients with Huntington’s disease, even in pre- or early-symptomatic stages of the disease, and…
Researchers have found a direct link between abnormal protein accumulation in nerve cells — a hallmark of several neurodegenerative diseases,…
Changes in the brain’s white matter in early Huntington’s disease can reflect a process that’s clinically relevant and might be…