A Genetic Lottery
— Rebecca Field

The Hereditary Disease Foundation (HDF) raised $900,000 to fund research into Huntington’s disease and other brain disorders during its Nov. 6 “Celebration of 50 Years of Discovery” symposium and gala at New York’s…

A protein responsible for protecting nerve cells can become embedded in other substances in the brains of  Huntington’s patients, preventing it from performing its neuroprotective work, Spanish researchers report. Another important finding was that…

The U.S. Patent and Trademark Office (USPTO) recently notified Mitochon Pharmaceuticals of its allowance on the first patent that the company says will help it proceed with the continued clinical development of…

The Huntington Society of Canada (HSC) and Ottawa-based social media company Shared have jointly launched the “One Extra Push” campaign to raise awareness about Huntington’s disease (HD) in Canada. Shared took up the challenge…

Researchers have identified an elaborate protein quality control system that prevents toxic accumulation of faulty proteins inside mitochondria, a phenomenon that underlies many neurodegenerative diseases, including Huntington’s disease. The study, ”Cytosolic Protein Vms1…

As therapeutics for Huntington’s disease (HD) are still a need, a number of natural compounds may hold promising beneficial effects, a review study shows. The review “The Medicinal Chemistry of Natural and Semi-Synthetic…

A Spanish study investigating the functioning of chloroplasts — the nutrient-producing “factory” of plants — has revealed a new mechanism that helps understand how a cell controls and regulates protein folding mechanisms. This new…

uniQure recently showed that its gene therapy candidate AMT-130 improves motor coordination and survival in mouse models of Huntington’s disease (HD). The preclinical study results were presented at the European Society of…

Researchers have come up with a new method to study the interactions between cell components that are thought to be defective in patients with Huntington’s disease and other neurodegenerative conditions. But while the…

Three Huntington’s disease (HD) patient advocacy organizations in Europe and North America recently launched a collaborative effort to give patients and the HD community more of a voice in clinical research. The newly formed Huntington’s…

The U.S. Food and Drug Administration (FDA) has awarded orphan drug status to uniQure’s proprietary candidate for Huntington’s disease (HD), a first in the history of Huntington’s treatment. No approved therapies exist to target…

Identifying Huntington’s disease progression can be a challenge in clinical trials. Now, an international team of researchers proposes in an article published in JAMA Neurology the use of a new composite measure to help…