Selecting Right Mouse Model Key for Huntington’s Research, Therapy Development, Study Finds

Certain aspects of Huntington’s disease (HD), such as the biologic mechanisms of depression, are not consistently replicated in mouse models of the disorder, which may hinder therapy development, a study reports. The study, “Increased Serotonin Transporter Expression in Huntington’s Disease Patients Is Not Consistently Replicated in Murine Models,”…

Brain Stimulation in Huntington’s Disease Promising, According to Study

Germany and UK-based researchers have found that a surgical implantation procedure known as pallidal deep brain stimulation was safe when placed into the brain for the reduction of movement problems in Huntington’s disease. The study could allow for more research examining the effectiveness of the technique in larger groups of people with the condition.