Katherine Poinsatte, PhD,  —

Sarepta Therapeutics has entered a global licensing and collaboration agreement with Arrowhead Pharmaceuticals covering Arrowhead’s therapy candidates, including ARO-HTT, an experimental treatment for Huntington’s disease. Sarepta will obtain exclusive global rights to ARO-HTT and other preclinical programs, as well as clinical and discovery-stage programs for rare genetic…

In Huntington’s disease (HD), progression is associated with metabolite changes in the brain that generally worsen as patients move from a presymptomatic stage to overt symptom onset, a review study reports. Its scientists looked at data from published studies analyzing metabolic changes in the brain between people with Huntington’s…