CAG repeats

May 30, 2019May 29, 2019

Tips from My Huntington’s Disease Genetic Testing Experience

Columns, Gene Positive - a Column by Steven Beatty

The identification of the Huntington’s disease (HD) gene in 1993 opened doors for new scientific exploration. The HD community of families and researchers around the world were excited about ... Read more

January 15, 2019January 15, 2019

Asuragen Launches AmplideX as Faster Diagnostic Test for Huntington’s Disease

News

Asuragen has launched a fast, easy-to-use and reliable diagnostic test, called AmplideX PCR/CE HTT Kit, for Huntington’s disease. The AmplideX test is able to detect up to more than 200 ... Read more

November 1, 2018November 1, 2018

Juvenile Huntington’s More Aggressive, Leads to Early Symptoms, Study Reports

News

The juvenile form of Huntington’s disease, which affects patients younger than 20, is particularly aggressive and associated with an early onset of symptoms, a retrospective study has found. Based on ... Read more

April 10, 2018April 10, 2018

HTT Mutations Seen to Cause Extensive Brain Remodeling, Affecting Motor and Cognitive Skills

News

Mutations linked to Huntington’s disease cause more extensive remodeling of functional connectivity in various regions of the brain than previously thought, affecting patients’ motor and cognitive skills, research looking ... Read more

March 20, 2018March 20, 2018

New Version of Genome Editing System Holds Potential to Treat Huntington’s

News

A modified version of the genome-editing CRISPR-Cas9 system may prevent the production of faulty huntingtin protein, moving closer to treatment for Huntington’s disease. The study, “Precise Excision of the ... Read more

December 15, 2016

Numerous DNA Repeats Seen in Huntington’s May be Result of Gene Repair Effort

News

Researchers may finally have tracked down an explanation for expansions of three-letter DNA sequences that disrupt genes, and lead to Huntington’s disease and numerous other neuromuscular and neurodegenerative conditions. The study, “The role ... Read more

November 22, 2016November 22, 2016

Number of CAG Repeats in Mutated Huntingtin Linked to Disease Onset in Study

News

Huntington’s disease is caused by excessive repeats of a portion of DNA, called CAG triplets, within the gene that codes for huntingtin (HTT). New research shows how the number of ... Read more

November 15, 2016November 15, 2016

Messenger RNA Seen as Potential New Treatment Target in Huntington’s

News

Researchers identified a new molecular mechanism related to mutant huntingtin (HTT) — messenger RNA — that may play a role in the development of Huntington’s disease. This finding may ... Read more

March 4, 2016March 4, 2016

Huntington’s Disease Therapies May Target Cholesterol Metabolism in Future

News

Huntington’s disease (HD) patients are known to have a dysregulation of cholesterol metabolism. Now, researchers have shown that manipulation of cholesterol levels in striatal neurons can improve motor deficits in ... Read more

November 20, 2015May 14, 2016

Huntington’s Gene Produces Cocktail of Mutant RAN Proteins

Huntington's Disease News, News

A group of researchers from the University of Florida Health have discovered new information about Huntington’s disease, namely that the gene causing this severe disorder causes an unforeseen accumulation of ... Read more

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