News

June 13, 2017

Researchers Propose NfL as New Blood Marker of Huntington’s Disease Onset, Progression

A factor called neurofilament light (NfL) may act as a biomarker of progression in Huntington’s disease, as blood levels of the molecule increase with more severe neurodegeneration. However, the ... Read more

June 8, 2017

Cell Transport ‘Traffic Jam’ Caused by Mutated Protein, Researchers Discover

News

A mutated form of the huntingtin (mHTT) protein has been acknowledged as the cause of Huntington’s disease, but researchers have not been fully clear about how it disrupts the ... Read more

June 6, 2017

Voyager Selects Gene Therapy Candidate for Huntington’s Clinical Trials

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Voyager Therapeutics has a new candidate for the treatment of Huntington’s disease. The selected gene therapy is called VY-HTT01 and aims to prevent the production of protein from the mutant huntingtin ... Read more

June 1, 2017June 1, 2017

Researchers Identify a Key Link Between the Brain’s Immune Cells and Neurodegenerative Disorders

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Researchers at the University of California and the Salk Institute for Biological Studies have identified the mechanisms that make the brain’s immune cells different from all other immune cells A ... Read more

May 30, 2017

Researchers Find Common Disease Processes in Huntington’s, Alzheimer’s and Parkinson’s

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Abnormal proteins found in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s seem to rely on the same mechanism to spread within the brain and disrupt its normal functions, ... Read more

May 25, 2017May 25, 2017

Neuroprotective Pathway May Be Key to Understanding Huntington’s Progression

News

A team of researchers has discovered new insights into cell processes that have gone awry in Huntingon’s disease (HD) patients. This discovery could point scientists toward a potential method ... Read more

May 23, 2017

University of Sussex Researchers Receive $3.37 Million to Develop Huntington’s Treatments

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Researchers at the Sussex Drug Discovery Centre in Brighton, England, have received a £3 million grant from Britain’s non-profit Wellcome Trust to develop Huntington’s disease treatments. The team will team up with other ... Read more

May 18, 2017

Researchers Discover Why Defects Form in Blood Brain Barrier of Huntington’s Patients

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Researchers have discovered why Huntington’s disease (HD) patients have defects in the blood-brain barrier that contribute to the symptoms of this neurological disorder. Their study, “Huntington’s Disease iPSC-Derived Brain ... Read more

May 16, 2017May 16, 2017

WAVE Life Sciences Continues Development of Two Drug Therapies for Huntington’s

News

WAVE Life Sciences’ products WVE-120101 (SNP-1) and WVE-120102 (SNP-2) will enter clinical trials in mid-2017 as part of the effort to develop new treatments for patients with Huntington’s disease. ... Read more

May 11, 2017May 11, 2017

Taube Philanthropies Donates $3 Million to Stanford, Gladstone for Huntington’s Research

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Taube Philanthropies has donated $3 million to fund a research team using gene editing and stem cell techniques to develop treatments for Huntington’s disease. The team is composed of Dr. Matthew ... Read more