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January 24, 2019January 24, 2019

Brain Neurons Disconnect from Each Other in Process Called Neuritosis, Mouse Study of Huntington’s Reveals

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The progressive death of brain nerve cells observed in Huntington’s disease is likely preceded by the retraction of their neurites — long projections that establish connections throughout the brain, a ... Read more

January 22, 2019January 22, 2019

Enrollment Completed for Phase 2 Trial Testing VX15/2503 in Early and Late Prodromal Huntington’s Patients

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Vaccinex has completed its target enrollment in a Phase 2 clinical trial assessing the potential of the investigational antibody VX15/2503 (pepinemab) as a treatment for patients with early manifest and late ... Read more

January 17, 2019January 17, 2019

Cerebellar Purkinje Cell Loss Linked to Huntington’s Motor Symptoms, Study Reports

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The loss of a type of nerve cell called a Purkinje cell in a brain region known as the neocerebellum is associated with the presentation of motor symptoms in Huntington’s ... Read more

January 15, 2019January 15, 2019

Asuragen Launches AmplideX as Faster Diagnostic Test for Huntington’s Disease

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Asuragen has launched a fast, easy-to-use and reliable diagnostic test, called AmplideX PCR/CE HTT Kit, for Huntington’s disease. The AmplideX test is able to detect up to more than 200 ... Read more

January 10, 2019January 10, 2019

Machine Learning Applied to EEG Data May Serve as Huntington’s Biomarker, Study Suggests

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A method called quantitative electroencephalography (qEEG) enables the identification of Huntington’s gene carriers and could become a disease biomarker, according to a pilot study. The research, “EEG may serve ... Read more

January 8, 2019January 8, 2019

Most Transplanted Fetal Nerve Cells in Brain of Huntington’s Patients Do Not Thrive, Study Says

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While transplanted fetal nerve cells can survive long term in the brain of a Huntington’s disease (HD) patient, only a specific subset called interneurons thrive, according to a study. ... Read more

January 3, 2019January 3, 2019

Huntexil Failed to Improve Motor Function of Huntington’s Patients in Phase 2 Trial

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Although well-tolerated, the investigational treatment Huntexil (pridopidine) failed to improve motor functions in a year-long Phase 2 clinical trial of Huntington’s patients. The research, “Safety and efficacy of pridopidine in ... Read more

December 21, 2018December 20, 2018

Rising Healthcare Costs Strain EU Budgets Even as New Therapies Flourish

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Cash-strapped governments across the 28-member European Union are struggling to control runaway healthcare expenditures — at exactly the same time as the promise of new but expensive therapies to ... Read more

December 20, 2018December 20, 2018

Gait, Balance Problems Can Help Diagnose Late-Onset Huntington’s, Study Finds

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Late-onset Huntington’s disease (emerging at age 59 or older), progresses similarly to common-onset Huntington’s except that late-onset patients more frequently showed gait and balance problems as their first symptom, new ... Read more

December 13, 2018December 13, 2018

European Huntington Association Promotes Awareness, Potential Gene Therapies

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There may be no cure yet for Huntington’s disease, but patients — and their families — can still do plenty to extend their life expectancy through proper diet, exercise, ... Read more

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